Pub. Date : 2008 Aug
PMID : 19967054
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, we report that the receptor interacting protein (RIP), a key adaptor protein of TNF signaling, was required to activate JNK in the cells treated with certain DNA damaging agents such as adriamycin (Adr) and 1-beta-D-arabinofuranosylcytosine (Ara-C) that cause slow and sustained activation, but it was not required when treated with N-methyl-N-nitro-N-nitrosoguanidine (MNNG) and short wavelength UV, which causes quick and transient activation. | Doxorubicin | tumor necrosis factor | Homo sapiens |