Title : Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition.

Pub. Date : 2010 Apr

PMID : 19961855






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 8Br-cGMP and SIL reduced ET1-stimulated TRPC6 expression and NFAT dephosphorylation (activity). 8-Bromoadenosine 5'-monophosphate transient receptor potential cation channel subfamily C member 6 Homo sapiens