Pub. Date : 2009 Dec 4
PMID : 19961596
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Identification of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation in association with neuroblastoma progression. | Tyrosine | matrix metallopeptidase 14 | Homo sapiens |
| 2 | METHODS: Tyrosine phosphorylated MT1-MMP was immunostained on tissue microarray samples from 55 patients with neuroblastoma detected by mass screening (known to be predominantly associated with favourable outcome), and from 234 patients with standard diagnosed neuroblastoma. | Tyrosine | matrix metallopeptidase 14 | Homo sapiens |
| 3 | CONCLUSION: Overall, these results suggest that tyrosine phosphorylated MT1-MMP plays an important role in neuroblastoma progression and that its expression is preferentially observed in tumor specimens from neuroblastoma patients showing poor clinical outcome. | Tyrosine | matrix metallopeptidase 14 | Homo sapiens |