Title : Opioid peptides derived from food proteins suppress aggregation and promote reactivation of partly unfolded stressed proteins.

Pub. Date : 2010 Feb

PMID : 19954758






1 Functional Relationships(s)
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1 The potential of small peptides derived from precursor food proteins, to bind to partly unfolded stressed proteins to prevent their irreversible aggregation and inactivation has been demonstrated in various in vitro test systems: dithiothreitol-induced aggregation of alpha-lactalbumin (LA), heat-induced aggregation of alcohol dehydrogenase (ADH), and aggregation and inactivation of bovine erythrocyte carbonic anhydrase (CA) in the process of its refolding after removal of stress conditions. Dithiothreitol lactalbumin alpha Bos taurus