Title : IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide.

Pub. Date : 2009 Nov 24

PMID : 19933982






1 Functional Relationships(s)
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1 METHODS: We retrospectively investigated the correlation of IDH1 and IDH2 mutations with overall survival and response to temozolomide in a cohort of patients with dedifferentiated low-grade astrocytomas treated with temozolomide at the time of progression after radiotherapy. Temozolomide isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens