Title : A Bre1-associated protein, large 1 (Lge1), promotes H2B ubiquitylation during the early stages of transcription elongation.

Pub. Date : 2010 Jan 22

PMID : 19923226






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Disruption of Lge1 abolished ubiquitylation of histone H2B on lysine 123 and H3 methylation on lysines 4 and 79 and resulted in significant sensitivity to 6-azauracil and mycophenolic acid. Lysine H2B clustered histone 21 Homo sapiens
2 Disruption of Lge1 abolished ubiquitylation of histone H2B on lysine 123 and H3 methylation on lysines 4 and 79 and resulted in significant sensitivity to 6-azauracil and mycophenolic acid. Lysine H2B clustered histone 21 Homo sapiens