Title : Phase I/II study of sequential therapy with irinotecan and S-1 for metastatic colorectal cancer.

Pub. Date : 2009 Dec 15

PMID : 19920821






4 Functional Relationships(s)
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1 BACKGROUND: Both irinotecan (CPT-11) and S-1 are active against colorectal cancer; however, as S-1 is a prodrug of 5-fluorouracil (5-FU), 5-FU and its metabolites might inhibit the antitumour effect of CPT-11. Irinotecan proteasome 26S subunit, non-ATPase 1 Homo sapiens
2 BACKGROUND: Both irinotecan (CPT-11) and S-1 are active against colorectal cancer; however, as S-1 is a prodrug of 5-fluorouracil (5-FU), 5-FU and its metabolites might inhibit the antitumour effect of CPT-11. Irinotecan proteasome 26S subunit, non-ATPase 1 Homo sapiens
3 BACKGROUND: Both irinotecan (CPT-11) and S-1 are active against colorectal cancer; however, as S-1 is a prodrug of 5-fluorouracil (5-FU), 5-FU and its metabolites might inhibit the antitumour effect of CPT-11. Irinotecan proteasome 26S subunit, non-ATPase 1 Homo sapiens
4 BACKGROUND: Both irinotecan (CPT-11) and S-1 are active against colorectal cancer; however, as S-1 is a prodrug of 5-fluorouracil (5-FU), 5-FU and its metabolites might inhibit the antitumour effect of CPT-11. Irinotecan proteasome 26S subunit, non-ATPase 1 Homo sapiens