Pub. Date : 2009 Dec 15
PMID : 19920821
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | BACKGROUND: Both irinotecan (CPT-11) and S-1 are active against colorectal cancer; however, as S-1 is a prodrug of 5-fluorouracil (5-FU), 5-FU and its metabolites might inhibit the antitumour effect of CPT-11. | Irinotecan | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |
2 | BACKGROUND: Both irinotecan (CPT-11) and S-1 are active against colorectal cancer; however, as S-1 is a prodrug of 5-fluorouracil (5-FU), 5-FU and its metabolites might inhibit the antitumour effect of CPT-11. | Irinotecan | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |
3 | BACKGROUND: Both irinotecan (CPT-11) and S-1 are active against colorectal cancer; however, as S-1 is a prodrug of 5-fluorouracil (5-FU), 5-FU and its metabolites might inhibit the antitumour effect of CPT-11. | Irinotecan | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |
4 | BACKGROUND: Both irinotecan (CPT-11) and S-1 are active against colorectal cancer; however, as S-1 is a prodrug of 5-fluorouracil (5-FU), 5-FU and its metabolites might inhibit the antitumour effect of CPT-11. | Irinotecan | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |