Title : Phosphorylation of alpha-actinin 4 upon epidermal growth factor exposure regulates its interaction with actin.

Pub. Date : 2010 Jan 22

PMID : 19920151






1 Functional Relationships(s)
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1 We expressed the two isoforms of human alpha-actinin in murine fibroblasts that express human epidermal growth factor receptor (EGFR) and found that both alpha-actinin 1 (ACTN1) and alpha-actinin 4 (ACTN4) were phosphorylated on tyrosine residues after stimulation with EGF, although ACTN4 was phosphorylated to the greater extent. Tyrosine actinin alpha 1 Homo sapiens