Title : The 1.4 A crystal structure of the class D beta-lactamase OXA-1 complexed with doripenem.

Pub. Date : 2009 Dec 22

PMID : 19919101






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The carboxylate attached to the beta-lactam ring of doripenem is stabilized by a salt bridge to K212 and a hydrogen bond with T213, in lieu of the interaction with an arginine side chain found in most other beta-lactamase-beta-lactam complexes (e.g., R244 in the class A member TEM-1). carboxylate CD248 molecule Homo sapiens