Pub. Date : 2010 Jan
PMID : 19910455
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Whereas TPA or TGF-beta alone stimulated VEGF promoter activity and up-regulated mRNA levels, significant protein secretion was detected only after RA was added to the culture systems. | Tetradecanoylphorbol Acetate | vascular endothelial growth factor A | Homo sapiens |
| 2 | Although the precise mechanism(s) of the RA effect remains to be defined, it appears to be mediated by reactive oxygen species; the antioxidant N-acetylcysteine inhibited RA+TPA-stimulated secretion of VEGF by more than 80%. | Tetradecanoylphorbol Acetate | vascular endothelial growth factor A | Homo sapiens |