Title : Regulation of heme synthesis and proteasomal activity by copper: possible implications for Wilson's disease.

Pub. Date : 2009

PMID : 19888908






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Exposure of HepG2 and Hep3B cells to Cu2+ inhibited the enzymes PBGD and ALAD of the heme synthesis pathway and, in parallel, upregulated heme oxygenase-1 (HO-1). cupric ion hydroxymethylbilane synthase Homo sapiens