Title : Aromatic interactions in the binding of ligands to HMGCoA reductase.

Pub. Date : 2009 Nov 5

PMID : 19863142






1 Functional Relationships(s)
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1 We examine potentially important enzyme-ligand interactions currently not incorporated into statin drug design: weak, induction/dispersion interactions between ligands and residue tyrosine 479 in the HMGCoA reductase active site. Tyrosine 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens