Title : Signal transduction pathways linking the activation of alveolar macrophages with the recruitment of neutrophils to lungs in chronic obstructive pulmonary disease.

Pub. Date : 2009 Aug

PMID : 19842832






1 Functional Relationships(s)
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1 These stimuli seem to activate mainly redox-sensitive transcription factors such as nuclear factor (NF)-kappa B and activator protein (AP)-1, both of which play a major role in the synthesis and secretion of chemotactic factors such as IL-8 and leukotriene B(4) (LTB(4)). Leukotriene B4 C-X-C motif chemokine ligand 8 Homo sapiens