Pub. Date : 2010 Jan
PMID : 19833896
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | OBJECTIVE: To test the hypothesis that free fatty acid (FFA) and muscle glycogen modify exercise-induced regulation of PDH (pyruvate dehydrogenase) in human skeletal muscle through regulation of PDK4 expression. | Fatty Acids, Nonesterified | pyruvate dehydrogenase phosphatase catalytic subunit 1 | Homo sapiens |
2 | OBJECTIVE: To test the hypothesis that free fatty acid (FFA) and muscle glycogen modify exercise-induced regulation of PDH (pyruvate dehydrogenase) in human skeletal muscle through regulation of PDK4 expression. | Fatty Acids, Nonesterified | pyruvate dehydrogenase phosphatase catalytic subunit 1 | Homo sapiens |
3 | The activation of PDH by exercise independent of changes in muscle glycogen or plasma FFA suggests that exercise overrules FFA-mediated inhibition of PDH (i.e., carbohydrate oxidation), and this may thus be one mechanism behind the health-promoting effects of exercise. | Fatty Acids, Nonesterified | pyruvate dehydrogenase phosphatase catalytic subunit 1 | Homo sapiens |