Title : Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety.

Pub. Date : 2009 Nov 12

PMID : 19821563






1 Functional Relationships(s)
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Protein Name
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1 As the substituent on the amide was increased in lipophilicity the potency and hERG inhibition increased, while polar groups lowered potency, without significantly impacting hERG inhibition. Amides ETS transcription factor ERG Homo sapiens