Title : Stoichiometries of transferrin receptors 1 and 2 in human liver.

Pub. Date : 2010 Jan 15

PMID : 19819738






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mutations in either the hereditary hemochromatosis protein, HFE, or transferrin receptor 2, TfR2, result in a similarly severe form of the most common type of iron overload disease called hereditary hemochromatosis. Iron transferrin receptor 2 Homo sapiens
2 Mutations in either the hereditary hemochromatosis protein, HFE, or transferrin receptor 2, TfR2, result in a similarly severe form of the most common type of iron overload disease called hereditary hemochromatosis. Iron transferrin receptor 2 Homo sapiens
3 Models of the interactions between HFE, TfR1, and TfR2 imply that these proteins are present in different molar concentrations in the liver, where they control expression of the iron regulatory hormone, hepcidin, in response to body iron loading. Iron transferrin receptor 2 Homo sapiens
4 Models of the interactions between HFE, TfR1, and TfR2 imply that these proteins are present in different molar concentrations in the liver, where they control expression of the iron regulatory hormone, hepcidin, in response to body iron loading. Iron transferrin receptor 2 Homo sapiens