Pub. Date : 2009 Nov 1
PMID : 19812204
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NaB, but not sodium formate, was found to inhibit LPS-induced expression of inducible NO synthase (iNOS), proinflammatory cytokines (TNF-alpha and IL-1beta) and surface markers (CD11b, CD11c, and CD68) in mouse microglia. | nab | nitric oxide synthase 2, inducible | Mus musculus |
| 2 | NaB, but not sodium formate, was found to inhibit LPS-induced expression of inducible NO synthase (iNOS), proinflammatory cytokines (TNF-alpha and IL-1beta) and surface markers (CD11b, CD11c, and CD68) in mouse microglia. | nab | nitric oxide synthase 2, inducible | Mus musculus |
| 3 | Similarly, NaB also inhibited fibrillar amyloid beta (Abeta)-, prion peptide-, double-stranded RNA (polyinosinic-polycytidylic acid)-, HIV-1 Tat-, 1-methyl-4-phenylpyridinium(+)-, IL-1beta-, and IL-12 p40(2)-induced microglial expression of iNOS. | nab | nitric oxide synthase 2, inducible | Mus musculus |
| 4 | In addition to microglia, NaB also suppressed the expression of iNOS in mouse peritoneal macrophages and primary human astrocytes. | nab | nitric oxide synthase 2, inducible | Mus musculus |