Title : Do we need still more trials on T4 and T3 combination therapy in hypothyroidism?

Pub. Date : 2009 Dec

PMID : 19808902






1 Functional Relationships(s)
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1 Development of a sustained-release T(3) preparation given as a single nighttime dose (together with levothyroxine once daily) might maintain physiological serum FT(4)-FT(3) ratio"s throughout 24 h. Genetic polymorphisms in deiodinase 2 and thyroid hormone transporters have been associated with well-being, fatigue, depression, and greater improvement on combination therapy. Triiodothyronine iodothyronine deiodinase 2 Homo sapiens