Title : Breast cancer-derived factors stimulate osteoclastogenesis through the Ca2+/protein kinase C and transforming growth factor-beta/MAPK signaling pathways.

Pub. Date : 2009 Nov 27

PMID : 19801662






1 Functional Relationships(s)
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1 In contrast, MDA-MB-231 factors induced phosphorylation of p38 and ERK1/2, and pharmacological inhibitors against p38 (SB203580) and MEK1/2 (PD98059) impeded the osteoclastogenic effects of cancer-derived factors. SB 203580 mitogen-activated protein kinase 3 Mus musculus