Title : The effect of malaria infection on the disposition of quinine and quinidine in the rat isolated perfused liver preparation.

Pub. Date : 1990 Jun

PMID : 1979624






1 Functional Relationships(s)
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1 Higher quinine (AUC:6470 +/- 1101 vs 3822 +/- 347 ng h mL-1, P less than 0.001) and quinidine (AUC: 6642 +/- 1304 vs 4808 +/- 872 ng h mL-1, P less than 0.05) concentrations were observed during malaria infection (MI). Quinine L1 cell adhesion molecule Mus musculus