Title : Hypoxia-induced decrease in p53 protein level and increase in c-jun DNA binding activity results in cancer cell resistance to etoposide.

Pub. Date : 2009 Oct

PMID : 19794957






1 Functional Relationships(s)
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1 siRNA-mediated silencing of c-jun increased the responsiveness of cells to etoposide under hypoxia, as shown by an increase in caspase 3 activity and lactate dehydrogenase release. Etoposide caspase 3 Homo sapiens