Title : Molecular evolution of specific human antibody against MUC1 mucin results in improved recognition of the antigen on tumor cells.

Pub. Date : 2009

PMID : 19776674






1 Functional Relationships(s)
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1 The resulting 12ESC-6 variants were shown to recognize not only the naked MUC1 tandem repeat but even more so glycosylated variants thereof, in particular those carrying the GalNAc (Tn) glycoform. N-acetylgalactosaminuronic acid mucin 1, cell surface associated Homo sapiens