Pub. Date : 2009 Sep 16
PMID : 19759305
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This unexpected finding coincides with POMC-cell-specific, Stat3-mediated upregulation of SOCS3 expression inhibiting both leptin and insulin signaling as insulin-stimulated PIP(3) (phosphatidylinositol-3,4,5 triphosphate) formation and protein kinase B (AKT) activation in POMC neurons as well as with the fact that insulin"s ability to hyperpolarize POMC neurons is largely reduced in POMC cells of Stat3-C(POMC) mice. | pip(3) | signal transducer and activator of transcription 3 | Mus musculus |