Title : Milk secretion of nitrofurantoin, as a specific BCRP/ABCG2 substrate, in assaf sheep: modulation by isoflavones.

Pub. Date : 2009 Oct

PMID : 19754918






2 Functional Relationships(s)
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1 The protein BCRP/ABCG2, present in the mammary epithelia, actively extrudes drugs into milk and can be modulated by isoflavones. Isoflavones ATP binding cassette subfamily G member 2 Bos taurus
2 All these results seem to point to a feasible control of drug secretion into milk through isoflavones in the diet when the drug is a good BCRP/ABCG2 substrate. Isoflavones ATP binding cassette subfamily G member 2 Bos taurus