Title : Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase.

Pub. Date : 2009 Oct 8

PMID : 19746975






2 Functional Relationships(s)
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1 Inhibition of soluble epoxide hydrolase (sEH) is hypothesized to lead to an increase in circulating levels of epoxyeicosatrienoic acids, resulting in the potentiation of their in vivo pharmacological properties. epoxyeicosatrienoic acids epoxide hydrolase 2 Rattus norvegicus
2 Inhibition of soluble epoxide hydrolase (sEH) is hypothesized to lead to an increase in circulating levels of epoxyeicosatrienoic acids, resulting in the potentiation of their in vivo pharmacological properties. epoxyeicosatrienoic acids epoxide hydrolase 2 Rattus norvegicus