Title : Integrin alpha(v)beta(3), metalloproteinases, and sphingomyelinase-2 mediate urokinase mitogenic effect.

Pub. Date : 2009 Dec

PMID : 19735728






2 Functional Relationships(s)
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1 We previously reported a role for the sphingolipid pathway in the mitogenic effect of plasminogen activators, but the signaling mechanisms involved in neutral sphingomyelinase-2 (NSMase-2) activation (the first step of the sphingolipid pathway) are poorly known. Sphingolipids sphingomyelin phosphodiesterase 3 Homo sapiens
2 We previously reported a role for the sphingolipid pathway in the mitogenic effect of plasminogen activators, but the signaling mechanisms involved in neutral sphingomyelinase-2 (NSMase-2) activation (the first step of the sphingolipid pathway) are poorly known. Sphingolipids sphingomyelin phosphodiesterase 3 Homo sapiens