Title : The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.

Pub. Date : 2009 Aug 28

PMID : 19716789






1 Functional Relationships(s)
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Protein Name
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1 Further, we show that low levels of Fbx6 and consequent impairment of replication stress-induced Chk1 degradation are associated with cancer cell resistance to the chemotherapeutic agent, camptothecin. Camptothecin checkpoint kinase 1 Homo sapiens