Title : Involvement of Phospholipase D 1 and 2 in the subcellular localization and activity of formyl-peptide-receptors in the human colonic cell line HT29.

Pub. Date : 2009 Aug

PMID : 19707939






1 Functional Relationships(s)
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1 In this study, we demonstrated that the depletion of PLD1 and 2 resulted in a marked reduction of formyl peptide receptor activity due to inhibited extracellular-signal regulated kinases 1/2 (ERK1/2), phosphorylation and cAMP level reduction. Cyclic AMP phospholipase D1 Homo sapiens