Title : The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.

Pub. Date : 2009 Sep 1

PMID : 19706762






2 Functional Relationships(s)
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1 The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. Nicotine cholinergic receptor nicotinic beta 4 subunit Homo sapiens
2 Genetic association studies have shown the importance of variants in the CHRNA5-CHRNA3-CHRNB4 cholinergic nicotinic receptor subunit gene cluster on chromosome 15q24-25.1 for the risk of nicotine dependence, smoking, and lung cancer in populations of European descent. Nicotine cholinergic receptor nicotinic beta 4 subunit Homo sapiens