Title : Contribution of CD4+CD25+ T cells to the regression phase of experimental autoimmune uveoretinitis.

Pub. Date : 2010 Jan

PMID : 19696173






2 Functional Relationships(s)
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1 METHODS: EAU was induced in B10RIII mice by immunization with IRBP(161-180) in complete Freund"s adjuvant and evaluated clinically and pathologically on days 0, 7, 14, 21, and 28. Water retinol binding protein 3, interstitial Mus musculus
2 Transfer of CD4(+)CD25(+) Treg cells obtained from EAU mice was able to suppress EAU induction by IRBP(161-180) that was not observed after transfer of cells from mice that had received CFA alone, suggesting antigen specificity of the Treg response. Water retinol binding protein 3, interstitial Mus musculus