Title : BRCA1 Expression is an Important Biomarker for Chemosensitivity: Suppression of BRCA1 Increases the Apoptosis via Up-regulation of p53 and p21 During Cisplatin Treatment in Ovarian Cancer Cells.

Pub. Date : 2007 Mar 2

PMID : 19690636






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 To address if BRCA1 expression plays a role in the chemotherapeutic response, we analyzed the effect of BRCA1 suppression on the sensitivity to cisplatin and paclitaxel in ovarian cancer cells. Paclitaxel BRCA1 DNA repair associated Homo sapiens