Title : Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease.

Pub. Date : 2010 Feb

PMID : 19690584






1 Functional Relationships(s)
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1 In this report we show that, in MPS IIIA fibroblasts, we were able to reduce mRNA levels of four genes, XYLT1, XYLT2, GALTI and GALTII, whose products are involved in GAG synthesis. Glycosaminoglycans xylosyltransferase 1 Homo sapiens