Title : Kinetic characterization of human phosphopantothenoylcysteine synthetase.

Pub. Date : 2009 Dec

PMID : 19683078






1 Functional Relationships(s)
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1 Oxygen transfer studies found that 18O from [carboxyl-18O] phosphopantothenate is incorporated into the AMP or CMP produced during PPCS catalysis, consistent with the formation of a phosphopantothenoyl cytidylate or phosphopantothenoyl adenylate intermediate, supporting similar catalytic mechanisms under both CTP and ATP conditions. Cytidine Monophosphate phosphopantothenoylcysteine synthetase Homo sapiens