Title : Erythropoietin, aluminium, and anaemia in patients on haemodialysis.

Pub. Date : 1990 Feb 3

PMID : 1967718






2 Functional Relationships(s)
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1 4 patients, who showed only a partial response to erythropoietin, had significantly higher serum aluminium concentrations than the 7 who responded fully (225 [44] vs 55 [23] micrograms/l); erythrocyte protoporphyrin concentrations in partial responders were also much higher than in responders (973 [120] vs 388 [29] nmol/l). Aluminum erythropoietin Homo sapiens
2 Aluminium intoxication may cause resistance to erythropoietin by interference with haem synthesis, with accumulation of protoporphyrin. Aluminum erythropoietin Homo sapiens