Title : Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90.

Pub. Date : 2009 Aug

PMID : 19671736






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 17-AAG down-regulated Rad51 and BRCA2 protein levels, abrogated induction of Rad51 foci by radiation, and inhibited HR measured by the I-Sce1 assay. tanespimycin RAD51 recombinase Homo sapiens
2 17-AAG down-regulated Rad51 and BRCA2 protein levels, abrogated induction of Rad51 foci by radiation, and inhibited HR measured by the I-Sce1 assay. tanespimycin RAD51 recombinase Homo sapiens