Title : Metabotropic glutamate mGluR5 receptor blockade opposes abnormal involuntary movements and the increases in glutamic acid decarboxylase mRNA levels induced by l-DOPA in striatal neurons of 6-hydroxydopamine-lesioned rats.

Pub. Date : 2009 Nov 10

PMID : 19660528






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Subchronic l-DOPA administration was paralleled by a significant increase in mRNA levels of the two isoforms of the GABA-synthesizing enzyme glutamic acid decarboxylase (GAD67 and GAD65) and preprodynorphin (PPD). Levodopa prodynorphin Rattus norvegicus