Title : Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7.

Pub. Date : 2009 Oct

PMID : 19655253






1 Functional Relationships(s)
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Protein Name
Organism
1 The inhibited structure of caspase-7/YVAD shows that the P4 Tyr binds the S4 region specific to polar residues at the expense of a main chain hydrogen bond between the P4 amide and carbonyl oxygen of caspase-7 Gln 276, which is similar to the caspase-3 complex. YVAD caspase 3 Homo sapiens