Title : Irinotecan therapy and molecular targets in colorectal cancer: a systemic review.

Pub. Date : 2009 Aug 7

PMID : 19653336






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Irinotecan sensitizes p53 wild type, mutant and null cells to Fas-mediated cell apoptosis in CRC cells. Irinotecan tumor protein p53 Homo sapiens
2 Wild type p53 cells were more sensitive to irinotecan than mutated p53. Irinotecan tumor protein p53 Homo sapiens
3 p53 and VEGF status of the patients" tumour is likely to affect the responsiveness of CRC to irinotecan. Irinotecan tumor protein p53 Homo sapiens