Title : Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice.

Pub. Date : 2009 Dec

PMID : 19647776






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Furthermore, pramipexole increased Bcl-2 immunoreactivity in DA neurons in the SNpc. Pramipexole B cell leukemia/lymphoma 2 Mus musculus
2 These results suggest that pramipexole may protect DA neurons against exposure to rotenone by chronic oral administration, and this effect is mediated by multiple functions including scavenging of *OH and induction of Bcl-2 protein. Pramipexole B cell leukemia/lymphoma 2 Mus musculus