Title : Methotrexate catabolism to 7-hydroxymethotrexate in rheumatoid arthritis alters drug efficacy and retention and is reduced by folic acid supplementation.

Pub. Date : 2009 Aug

PMID : 19644884






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RESULTS: Folic acid inhibited aldehyde oxidase (AO), the enzyme that produces 7-OH-MTX, but folinic acid did not. 7-hydroxymethotrexate aldehyde oxidase 1 Homo sapiens
2 RESULTS: Folic acid inhibited aldehyde oxidase (AO), the enzyme that produces 7-OH-MTX, but folinic acid did not. 7-hydroxymethotrexate aldehyde oxidase 1 Homo sapiens