Pub. Date : 2009 Aug
PMID : 19639579
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The SP- and IGF-1-induced up-regulation of ZO-1 was accompanied by phosphorylation of extracellular signal-regulated kinase (ERK), and both of these effects were blocked by PD98059, an inhibitor of ERK activation. | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | insulin like growth factor 1 | Homo sapiens |
2 | SP and IGF-1 also increased the transepithelial electrical resistance (TER) (an indicator of barrier function) of an A431 cell monolayer in a manner sensitive to PD98059. | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | insulin like growth factor 1 | Homo sapiens |