Title : Poly I:C-induced activation of NK cells by CD8 alpha+ dendritic cells via the IPS-1 and TRIF-dependent pathways.

Pub. Date : 2009 Aug 15

PMID : 19635904






1 Functional Relationships(s)
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1 In this study, we demonstrate that the IPS-1-dependent and the TRIF-dependent pathways are essential for NK cell activation to poly I:C stimulation in mice, whereas deficiency in either IPS-1 or TRIF only modestly impairs the poly I:C-induced NK cell activation. Poly I-C toll-like receptor adaptor molecule 1 Mus musculus