Title : The protective effect of irbesartan in rats fed a high fat diet is associated with modification of leptin-adiponectin imbalance.

Pub. Date : 2009 Aug

PMID : 19633450






3 Functional Relationships(s)
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1 The protective effect of irbesartan in rats fed a high fat diet is associated with modification of leptin-adiponectin imbalance. Irbesartan adiponectin, C1Q and collagen domain containing Rattus norvegicus
2 The leptin/adiponectin ratio of plasma concentrations and protein expression in lumbar adipose tissue increased (P < 0.05) in HFD rats, and were normalized by irbesartan. Irbesartan adiponectin, C1Q and collagen domain containing Rattus norvegicus
3 The correction of leptin-adiponectin imbalance may be an important mechanism participating in the protective effect of irbesartan in HFD rats. Irbesartan adiponectin, C1Q and collagen domain containing Rattus norvegicus