Title : An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells.

Pub. Date : 2010 Feb 5

PMID : 19631715






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Natural ligands have not been identified, however, recent reports have demonstrated the synthetic phenolic acyl hydrazone, GSK4716, functions as a selective ERRbeta/gamma agonist. GSK 4716 estrogen related receptor beta Homo sapiens
2 Treatment of differentiated skeletal muscle cells with the ERRbeta/gamma agonist (GSK4716) produced a significant increase in the expression of GRalpha (isoform D) protein. GSK 4716 estrogen related receptor beta Homo sapiens