Title : Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme.

Pub. Date : 2009 Sep 25

PMID : 19622750






2 Functional Relationships(s)
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1 We show that chimeric gp43-UL54 enzymes that contain residues of helix N and helix P of UL54 are resensitized against foscarnet and acyclovir. Acyclovir DNA polymerase catalytic subunit Human betaherpesvirus 5
2 We show that chimeric gp43-UL54 enzymes that contain residues of helix N and helix P of UL54 are resensitized against foscarnet and acyclovir. Acyclovir DNA polymerase catalytic subunit Human betaherpesvirus 5