Title : Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms.

Pub. Date : 2009 Oct 1

PMID : 19592582






2 Functional Relationships(s)
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Protein Name
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1 Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms. Iron transmembrane serine protease 6 Homo sapiens
2 Mutations leading to abrogation of matriptase-2 proteolytic activity in humans are associated with an iron-refractory iron deficiency anemia (IRIDA) due to elevated hepcidin levels. Iron transmembrane serine protease 6 Homo sapiens