Title : Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis.

Pub. Date : 2009 Oct

PMID : 19591830






1 Functional Relationships(s)
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1 However, levels of hepatic phosphorylated Smad 1/5/8 protein (an intracellular mediator of Bmp6 signaling) and Id1 mRNA (a target gene of Bmp6) were inappropriately low for the body iron burden and Bmp6 mRNA levels in Hfe KO, compared with WT mice. Iron inhibitor of DNA binding 1, HLH protein Mus musculus