Title : Organotypic cultures of prepubertal mouse testes: a method to study androgen action in sertoli cells while preserving their natural environment.

Pub. Date : 2009 Dec

PMID : 19587329






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Testis morphology and androgen induction of the studied genes were preserved for 48 h. Preincubation with ketoconazole for 24 h to block endogenous androgen production, followed by 24-h incubation with the synthetic androgen R1881, resulted in 45-, 5-, 19-, and 6-fold induction of mRNA levels of Rhox5, Spinlw1, Gpd1, and Drd4, respectively. Ketoconazole glycerol-3-phosphate dehydrogenase 1 (soluble) Mus musculus