Pub. Date : 2009 Jul 15
PMID : 19567673
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | When gefitinib (200 mg/kg) was preadministered to inhibit Bcrp1 and P-gp, the vCSF-to-plasma ratio decreased to 1.29 +/- 0.09 in wild-type mice and increased to 1.13 +/- 0.13 in Mdr1a/b(-/-)Bcrp1(-/-) mice, whereas the ECF-to-plasma ratio increased to 0.74 +/- 0.14 in wild-type and 1.07 +/- 0.03 in Mdr1a/b(-/-)Bcrp1(-/-) mice. | Gefitinib | phosphoglycolate phosphatase | Mus musculus |