Pub. Date : 2009 Sep
PMID : 19545278
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Morphine withdrawal regulates phosphorylation of cAMP response element binding protein (CREB) through PKC in the nucleus tractus solitarius-A2 catecholaminergic neurons. | Morphine | protein kinase C, gamma | Rattus norvegicus |
| 2 | Morphine withdrawal modulates gene expression in the NTS through various second-messenger signal transduction systems including activation of extracellular signal-regulated kinases 1/2 (ERK(1/2)) and protein kinase C (PKC). | Morphine | protein kinase C, gamma | Rattus norvegicus |
| 3 | Morphine withdrawal modulates gene expression in the NTS through various second-messenger signal transduction systems including activation of extracellular signal-regulated kinases 1/2 (ERK(1/2)) and protein kinase C (PKC). | Morphine | protein kinase C, gamma | Rattus norvegicus |
| 4 | The results indicate that PKC mediates both CREB activation and HPA response by morphine withdrawal and might suggest that CREB activation in the NTS is related to TH expression associated with morphine withdrawal. | Morphine | protein kinase C, gamma | Rattus norvegicus |
| 5 | The results indicate that PKC mediates both CREB activation and HPA response by morphine withdrawal and might suggest that CREB activation in the NTS is related to TH expression associated with morphine withdrawal. | Morphine | protein kinase C, gamma | Rattus norvegicus |